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Mikhail Krasavin Selected Research

Anhydrides

12/2021Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).
1/2018Design, in silico prioritization and biological profiling of apoptosis-inducing lactams amenable by the Castagnoli-Cushman reaction.

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Mikhail Krasavin Research Topics

Disease

21Neoplasms (Cancer)
12/2022 - 12/2016
4Glaucoma
12/2022 - 01/2016
4Type 2 Diabetes Mellitus (MODY)
04/2021 - 01/2016
3Neuralgia (Stump Neuralgia)
12/2021 - 01/2016
2Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
01/2021 - 09/2018
2Hypoxia (Hypoxemia)
12/2020 - 02/2019
2Iron Overload
02/2019 - 12/2017
2Edema (Dropsy)
01/2016 - 09/2014
1Adenocarcinoma of Lung
01/2022
1Neoplasm Metastasis (Metastasis)
12/2021
1Acquired Immunodeficiency Syndrome (AIDS)
12/2021
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2021
1Urinary Bladder Neoplasms (Bladder Cancer)
10/2021
1autosomal dominant Spastic paraplegia 6
10/2021
1Inflammation (Inflammations)
08/2021
1Lung Injury
08/2021
1Infections
08/2021
1Insulinoma
04/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2020
1Arthritis (Polyarthritis)
12/2020
1Glioblastoma (Glioblastoma Multiforme)
04/2020
1Glioma (Gliomas)
01/2020
1Adenocarcinoma
04/2019
1Communicable Diseases (Infectious Diseases)
04/2019
1Autoimmune Diseases (Autoimmune Disease)
01/2019
1Human Influenza (Influenza)
01/2019
1Rheumatoid Arthritis
01/2019
1Tuberculosis (Tuberculoses)
09/2018
1Diabetes Mellitus
12/2017
1Seizures (Absence Seizure)
10/2017
1Central Nervous System Diseases (CNS Diseases)
06/2017
1Ocular Hypertension (Glaucoma, Suspect)
01/2017

Drug/Important Bio-Agent (IBA)

15Protein Isoforms (Isoforms)IBA
12/2022 - 01/2016
12Carbonic Anhydrases (Carbonic Anhydrase)IBA
12/2022 - 01/2016
7SulfonamidesIBA
12/2021 - 01/2016
6Pharmaceutical PreparationsIBA
01/2022 - 06/2015
5Thioredoxin-Disulfide ReductaseIBA
06/2021 - 01/2020
4EnzymesIBA
01/2022 - 04/2019
3Carbonic Anhydrase InhibitorsIBA
12/2022 - 01/2017
3Carbonic Anhydrase IXIBA
12/2021 - 04/2019
3Nonesterified Fatty Acids (NEFA)IBA
04/2021 - 01/2016
3BenzenesulfonamidesIBA
11/2019 - 10/2017
3ImidazolinesIBA
04/2019 - 10/2017
3Biological ProductsIBA
01/2016 - 09/2014
2ThioredoxinsIBA
01/2022 - 01/2020
2CoumarinsIBA
12/2021 - 10/2021
2BenzopyransIBA
12/2021 - 10/2021
2CaspasesIBA
12/2021 - 10/2021
2AnhydridesIBA
12/2021 - 01/2018
2IsoenzymesIBA
06/2021 - 12/2020
2SelenocysteineIBA
06/2021 - 11/2019
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
04/2020 - 01/2020
2Carbonic Anhydrase IIIBA
11/2019 - 01/2017
2LY2881835IBA
12/2017 - 11/2016
2Metabotropic Glutamate 5 ReceptorIBA
06/2017 - 01/2017
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2016 - 01/2016
1AntioxidantsIBA
01/2022
1NitrogenIBA
01/2022
1Cytostatic AgentsIBA
01/2022
1Free RadicalsIBA
01/2022
1Drug CombinationsIBA
12/2021
1Proteins (Proteins, Gene)FDA Link
12/2021
1ZincIBA
12/2021
1Reverse Transcriptase InhibitorsIBA
12/2021
1elsulfavirineIBA
12/2021
1ammonium acetateIBA
12/2021
1NucleosidesIBA
12/2021
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2021
1ProdrugsIBA
12/2021
1Caspase 3 (Caspase-3)IBA
10/2021
1coumarinIBA
10/2021
1PiperidinesIBA
04/2021
1TAK-875IBA
04/2021
1Glucose (Dextrose)FDA LinkGeneric
04/2021
1OPC-67683IBA
01/2021
1pretomanidIBA
01/2021
1NitroimidazolesIBA
01/2021
1Antineoplastic Agents (Antineoplastics)IBA
12/2020
1DNA (Deoxyribonucleic Acid)IBA
12/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2019
1Thioredoxin Reductase 1IBA
11/2019
1pyridazineIBA
04/2019
1Benzene (Benzole)IBA
04/2019
1Monoamine Oxidase (MAO)IBA
04/2019
1OxadiazolesIBA
04/2019
1Hydroxamic Acids (Hydroxamic Acid)IBA
02/2019
1IronIBA
02/2019
1phenylideneIBA
01/2019
1Messenger RNA (mRNA)IBA
01/2019
1EndonucleasesIBA
01/2019
1Cycloserine (Seromycin)FDA Link
09/2018
1LactamsIBA
01/2018
1Transcription Factors (Transcription Factor)IBA
01/2018
1IminesIBA
01/2018
1Chelating AgentsIBA
12/2017
1SiderophoresIBA
12/2017
1Anti-Bacterial Agents (Antibiotics)IBA
12/2017
1LigandsIBA
02/2017

Therapy/Procedure

6Therapeutics
01/2022 - 12/2017
3Drug Therapy (Chemotherapy)
12/2021 - 01/2017